In a randomized, placebo-controlled crossover study with five volunteers who had atherosclerotic cardiovascular disease, we explored the effects of increasing lecithin cholesterol acyltransferase (LCAT) activity on fat metabolism.
While we found that a short-term boost in LCAT enhances the conversion of free cholesterol into cholesteryl esters, it did not significantly change the levels of key HDL proteins or affect the metabolism of other lipoproteins.
Ultimately, although LCAT might help improve cholesterol balance over time, there wasn't a clear immediate benefit proven for heart health.
Read More
8
Effects of HDL size on CEC
Flipped C-Terminal Ends of APOA1 Promote ABCA1-Dependent Cholesterol Efflux by Small HDLs.
We investigated how different sizes of HDL particles affect cholesterol efflux capacity (CEC), a key indicator of cardiovascular health. Our model studies revealed that smaller HDL particles have a unique structure that enhances their ability to promote CEC through interaction with the ABCA1 pathway.
Interestingly, even subjects with low HDL levels exhibited normal CEC, indicating the importance of particle size. The small HDL particles demonstrated a 3- to 5-fold increase in CEC compared to larger ones. This suggests that fostering small HDL particles could potentially lower cardiovascular disease risk, highlighting their cardioprotective properties.
Read More
8
Lecithin improves children's heart health
INTEGRATIVE MORPHOMETRIC CHARACTERISTIC OF ENDOTHELIAL DYSFUNCTION IN THE CASES OF CHILDREN WITH ESSENTIAL ARTERIAL HYPERTENSION.
We conducted an in-depth study involving 80 children diagnosed with Essential Arterial Hypertension and related endothelial dysfunction.
The children received either standard treatment or an improved regimen that included lecithin. Over two months, we observed significant benefits in heart function and reduced complications.
Those on optimized treatment showed improvements in heart volume and reduced vascular dysfunction. This suggests that lecithin can positively influence cardiovascular health in children facing these conditions.
Read More
Most Useful Reviews
9
Boosts immune system
41 people found this helpful
Lecithin is essential for me and my husband; we specifically chose sunflower as it’s free from harmful phytoestrogens. Its high levels of oleic and linoleic acids are known to lower cardiovascular disease risk and support immunity. Thanks to lecithin, my cholesterol levels are decreasing, and it aids in fat oxidation and metabolism.
Read More
9
Natural cholesterol support
13 people found this helpful
Sunflower lecithin has been a reliable method for managing my cholesterol levels. Regular use has effectively improved my cholesterol profile, particularly in reducing harmful types. I’m thrilled with its natural support for my cardiovascular health and would recommend it to anyone looking for a safe and effective supplement.
Read More
9
Supports cardiovascular health
2 people found this helpful
Found what I was looking for! Sunflower Lecithin 1200 mg is a great supplement to support your health! ✨ I take 2 capsules every morning to restore my liver and prevent stone formation, as lecithin contains phosphatidylcholine, which aids liver and nervous system function. ✅ Supports the liver - promotes cell regeneration and improves fat metabolism, helps prevent gallstones. ✅ Useful for the nervous system - supports brain function, improves memory and concentration. ✅ Positively affects the cardiovascular system - helps reduce "bad" cholesterol. ✅ GMO-free, sunflower is a great alternative to soy lecithin. I like that this lecithin is in soft capsules that are easy to swallow. If you seek natural support for your liver, brain, and heart, I recommend this product!
We examined how lower levels of lecithin-cholesterol acyltransferase (LCAT) activity could impact cardiovascular health in patients with chronic kidney disease (CKD). This study involved 453 non-dialysis CKD patients and monitored them for about five years.
We found that low LCAT activity is linked to higher risks of death and acute decompensated heart failure, suggesting a protective role of certain HDL particles. However, interestingly, LCAT levels did not seem to affect atherosclerotic events or kidney function declines.
Read More
8
Effects of HDL size on CEC
Flipped C-Terminal Ends of APOA1 Promote ABCA1-Dependent Cholesterol Efflux by Small HDLs.
We investigated how different sizes of HDL particles affect cholesterol efflux capacity (CEC), a key indicator of cardiovascular health. Our model studies revealed that smaller HDL particles have a unique structure that enhances their ability to promote CEC through interaction with the ABCA1 pathway.
Interestingly, even subjects with low HDL levels exhibited normal CEC, indicating the importance of particle size. The small HDL particles demonstrated a 3- to 5-fold increase in CEC compared to larger ones. This suggests that fostering small HDL particles could potentially lower cardiovascular disease risk, highlighting their cardioprotective properties.
Read More
8
Lecithin improves children's heart health
INTEGRATIVE MORPHOMETRIC CHARACTERISTIC OF ENDOTHELIAL DYSFUNCTION IN THE CASES OF CHILDREN WITH ESSENTIAL ARTERIAL HYPERTENSION.
We conducted an in-depth study involving 80 children diagnosed with Essential Arterial Hypertension and related endothelial dysfunction.
The children received either standard treatment or an improved regimen that included lecithin. Over two months, we observed significant benefits in heart function and reduced complications.
Those on optimized treatment showed improvements in heart volume and reduced vascular dysfunction. This suggests that lecithin can positively influence cardiovascular health in children facing these conditions.
Read More
8
Lecithin shows promise for cholesterol management
MEDI6012: Recombinant Human Lecithin Cholesterol Acyltransferase, High-Density Lipoprotein, and Low-Density Lipoprotein Receptor-Mediated Reverse Cholesterol Transport.
We investigated how MEDI6012, a recombinant human lecithin cholesterol acyltransferase, could impact heart health in patients with stable coronary heart disease. In a phase 2 clinical trial, 48 participants received either MEDI6012 or a placebo, with various doses administered through intravenous and subcutaneous methods.
Our results showed that while MEDI6012 was effective at increasing high-density lipoprotein (HDL) cholesterol levels, there were no significant safety concerns compared to placebo. Overall, it appears that lecithin treatment could enhance the body’s cholesterol handling but further research is needed before it can be routinely recommended.
Read More
7
Effects of LCAT on cholesterol metabolism
Effects of Recombinant Human Lecithin Cholesterol Acyltransferase on Lipoprotein Metabolism in Humans.
In a randomized, placebo-controlled crossover study with five volunteers who had atherosclerotic cardiovascular disease, we explored the effects of increasing lecithin cholesterol acyltransferase (LCAT) activity on fat metabolism.
While we found that a short-term boost in LCAT enhances the conversion of free cholesterol into cholesteryl esters, it did not significantly change the levels of key HDL proteins or affect the metabolism of other lipoproteins.
Ultimately, although LCAT might help improve cholesterol balance over time, there wasn't a clear immediate benefit proven for heart health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 43 Reviews
7.5
All Reviews
Positive Reviews
Negative Reviews
9
Boosts immune system
41 people found this helpful
Lecithin is essential for me and my husband; we specifically chose sunflower as it’s free from harmful phytoestrogens. Its high levels of oleic and linoleic acids are known to lower cardiovascular disease risk and support immunity. Thanks to lecithin, my cholesterol levels are decreasing, and it aids in fat oxidation and metabolism.
Read More
9
Natural cholesterol support
13 people found this helpful
Sunflower lecithin has been a reliable method for managing my cholesterol levels. Regular use has effectively improved my cholesterol profile, particularly in reducing harmful types. I’m thrilled with its natural support for my cardiovascular health and would recommend it to anyone looking for a safe and effective supplement.
Read More
9
Supports cardiovascular health
2 people found this helpful
Found what I was looking for! Sunflower Lecithin 1200 mg is a great supplement to support your health! ✨ I take 2 capsules every morning to restore my liver and prevent stone formation, as lecithin contains phosphatidylcholine, which aids liver and nervous system function. ✅ Supports the liver - promotes cell regeneration and improves fat metabolism, helps prevent gallstones. ✅ Useful for the nervous system - supports brain function, improves memory and concentration. ✅ Positively affects the cardiovascular system - helps reduce "bad" cholesterol. ✅ GMO-free, sunflower is a great alternative to soy lecithin. I like that this lecithin is in soft capsules that are easy to swallow. If you seek natural support for your liver, brain, and heart, I recommend this product!
Read More
9
Reduces cholesterol levels
1 people found this helpful
I chose this lecithin for both my husband and me because men should avoid soy lecithin due to estrogens. 🌿 Sunflower is GMO-free and contains more oleic and linoleic acids, reducing cardiovascular disease risk. 🌿 It supports immunity with fatty acids that have anti-inflammatory properties. 🌿 Lecithin decreases already deposited cholesterol by an average of 20% and activates removal processes, aiding in weight loss by oxidising fat cells.
Read More
9
Essential nutrient
1 people found this helpful
Ideal for men! Lecithin is crucial for nerves, comprising 17% of the peripheral nervous system and 30% of the brain. Its deficiency leads to irritability, fatigue, and even nervous breakdowns. Lecithin accelerates oxidative processes, ensures proper fat metabolism, enhances brain and cardiovascular system functions, aids vitamin absorption, and boosts resistance to toxins. This specific lecithin is ideal for men as it contains no soy!
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Lecithin is a natural substance that is found in various plant and animal tissues, primarily derived from soybeans, eggs, or sunflower seeds. It is a phospholipid, which means it contains both a hydrophilic (water-attracting) and hydrophobic (water-repellent) component. This unique structure makes lecithin an excellent emulsifier, which allows it to blend ingredients that typically don't mix well together, such as oil and water. As a result, it is commonly used in food products, cosmetics, and nutritional supplements to improve texture, stability, and shelf life.
In food products, lecithin can be found in a wide range of items, from chocolates to baked goods, providing a smoother mouthfeel and enhancing flavor distribution. Additionally, lecithin plays a role in promoting better absorption of certain nutrients in the body, which has led to its popularity as a dietary supplement. While lecithin is generally considered safe for consumption, those with soy allergies should opt for alternatives like sunflower lecithin. Whether you're a home cook looking to improve your dishes or someone interested in the potential health benefits, understanding lecithin's versatile uses can enhance your culinary and nutritional knowledge.
Lecithin is a fatty substance found in many foods, including soybeans, egg yolks, and sunflower seeds, and it has been studied for its potential health benefits, particularly for cardiovascular health. Some research suggests that lecithin may help lower cholesterol levels, which is a significant factor in heart disease. Lecithin contains phosphatidylcholine, which aids in breaking down and transporting fats in the body. However, while there may be some benefits associated with lecithin, such as improved lipid profiles, the evidence is still inconclusive regarding its effectiveness in significantly reducing the risk of cardiovascular disease.
It's important to note that lecithin should not be seen as a replacement for prescribed medications or evidence-based lifestyle changes, such as a heart-healthy diet and regular exercise. If you're considering adding lecithin to your regimen for cardiovascular health, it's crucial to consult with a healthcare provider to ensure it fits within your individual health plan and to address any potential interactions with other medications. Additionally, focusing on overall dietary patterns—rich in fruits, vegetables, whole grains, and healthy fats—remains the best strategy for managing heart health.
Based on user reviews, it typically takes around 2 to 3 months of consistent use before noticeable results are observed when taking sunflower lecithin for cardiovascular health. One user mentioned, "To see results, it should be consumed for 2-3 months" Read Review. Another user remarked on their positive experiences after two months of daily intake, indicating improvement in their health conditions Read Review.
Many users noted enhancements in their cholesterol levels and overall cardiovascular function with regular intake. For instance, a user shared that regular use had effectively improved their cholesterol profile Read Review, while another stated that they witnessed significant improvements in circulation Read Review. However, individual responses can vary, and it's advisable to consult a healthcare provider for personalized recommendations.
Lecithin shows some promise in supporting cardiovascular health, although research findings are mixed and sometimes inconclusive. A study involving children with hypertension indicated that lecithin might improve heart function and reduce vascular complications, suggesting potential benefits for cardiovascular health in specific populations [4]. Additionally, research in chronic kidney disease patients highlighted the role of lecithin-cholesterol acyltransferase (LCAT) activity, noting that low levels are associated with increased cardiac risks [1].
However, other studies suggest that while lecithin can enhance cholesterol metabolism, no immediate heart health benefits were observed, and its impact on other lipoproteins remains unclear [2]. Another phase 2 clinical trial showed that lecithin treatment could raise HDL cholesterol levels without significant adverse effects, yet it emphasized the necessity for further investigations before it becomes a standard recommendation [5]. Overall, while some studies indicate potential cardiovascular benefits, more robust clinical evidence is required to firmly establish lecithin as a beneficial supplement for cardiovascular disease.
Users frequently report a variety of improvements in symptoms related to cardiovascular health and overall wellness when taking sunflower lecithin. Many individuals note significant reductions in their cholesterol levels, with one user indicating a 20% decrease in already deposited cholesterol and others expressing satisfaction with improved cholesterol profiles Read Review, Read Review. Enhanced circulation is another cited benefit, with a user specifically stating that their circulation had significantly improved after consistent use Read Review. The supplement is praised for its role in promoting fat oxidation and metabolism, which many users attribute to its positive effects on weight management as well Read Review.
In addition to cardiovascular benefits, users have reported improvements in cognitive function and liver health. Several reviews highlight enhancements in memory and brain function, particularly for those concerned about age-related decline Read Review. Sunflower lecithin is noted for its ability to support liver function and possibly alleviate digestive issues Read Review. Overall, while user experiences vary, those who consistently use sunflower lecithin commend its multifaceted benefits, including improvements in cholesterol levels, liver and brain function, and general well-being.
Users have shared various experiences when combining sunflower lecithin with other supplements to support cardiovascular health. Many report positive interactions with their existing routines. For instance, one user noted that sunflower lecithin has significantly improved their cholesterol levels while using it alongside other health measures, emphasizing its ability to lower bad cholesterol and improve overall heart function Read Review. Another review highlights the benefits of lecithin in enhancing fat metabolism, particularly when combined with a balanced diet and exercise, which also aids in weight management Read Review. Users frequently emphasize that this supplement complements their overall wellness strategies, particularly in ages above 35, who appreciate its multifaceted benefits Read Review.
Based on user reviews, a commonly recommended dosage for sunflower lecithin, particularly for supporting cardiovascular health, is two capsules daily. Several users noted that this dosage has contributed positively to their cholesterol levels and overall heart health. For instance, one user highlights taking two capsules every morning, mentioning how it has helped restore their liver and maintain cardiovascular wellness Read Review. Another review supports this recommendation, indicating that two daily capsules are sufficient for experiencing the benefits while being easy to swallow Read Review.
Additionally, users have reported that regular intake of sunflower lecithin can lead to improvements in cholesterol profiles, particularly in reducing "bad" cholesterol levels and mitigating cardiovascular disease risks Read Review. This aligns with the beneficial properties attributed to its rich content of omega-9 fatty acids Read Review. Overall, users seem to agree that a daily intake of two capsules can provide significant support for cardiovascular health.
7.5
Enhances memory improvement
1 people found this helpful
The quality is fantastic! This lecithin is excellent for those over 35. To see results, it should be consumed for 2-3 months. It helps improve memory and brain function, especially after cardiovascular diseases. The capsules are slightly larger but manageable with water. Dosage should be discussed with a doctor.
7.5
Detoxification aid
1 people found this helpful
Lecithin serves as a hepatoprotector, particularly for liver issues such as hepatitis and digestive disorders. I’ve been taking it for two months, two capsules daily, and I appreciate the positive effects. The duration should be personalised based on individual health conditions. Sunflower lecithin is recommended for those allergic to egg or soy.
9
Natural cholesterol support
13 people found this helpful
Sunflower lecithin has been a reliable method for managing my cholesterol levels. Regular use has effectively improved my cholesterol profile, particularly in reducing harmful types. I’m thrilled with its natural support for my cardiovascular health and would recommend it to anyone looking for a safe and effective supplement.
7.5
Improved circulation
1 people found this helpful
Sunflower Lecithin 1200mg is a high-quality product that offers cardiovascular benefits. Since using it, my circulation has significantly improved. I appreciate that it is soy-free and that the capsules are an adequate size—1-2 capsules daily suffice. NOW Sunflower Lecithin contains phosphatidylcholine, the primary phospholipid found in cell membranes, which plays a vital role in cell signalling and function. This supplement is also rich in other important phospholipids, aiding fat dispersion in water and absorption by the body. The softgels are non-GMO and soy-free.
9
Reduces cholesterol levels
1 people found this helpful
I chose this lecithin for both my husband and me because men should avoid soy lecithin due to estrogens. 🌿 Sunflower is GMO-free and contains more oleic and linoleic acids, reducing cardiovascular disease risk. 🌿 It supports immunity with fatty acids that have anti-inflammatory properties. 🌿 Lecithin decreases already deposited cholesterol by an average of 20% and activates removal processes, aiding in weight loss by oxidising fat cells.
9
Boosts immune system
41 people found this helpful
Lecithin is essential for me and my husband; we specifically chose sunflower as it’s free from harmful phytoestrogens. Its high levels of oleic and linoleic acids are known to lower cardiovascular disease risk and support immunity. Thanks to lecithin, my cholesterol levels are decreasing, and it aids in fat oxidation and metabolism.
7.5
Supports liver health
129 people found this helpful
Lecithin has proven to be an excellent aid for my liver and gallbladder problems. It’s significantly helped improve my condition.
9
Supports cardiovascular health
2 people found this helpful
Found what I was looking for! Sunflower Lecithin 1200 mg is a great supplement to support your health! ✨ I take 2 capsules every morning to restore my liver and prevent stone formation, as lecithin contains phosphatidylcholine, which aids liver and nervous system function. ✅ Supports the liver - promotes cell regeneration and improves fat metabolism, helps prevent gallstones. ✅ Useful for the nervous system - supports brain function, improves memory and concentration. ✅ Positively affects the cardiovascular system - helps reduce "bad" cholesterol. ✅ GMO-free, sunflower is a great alternative to soy lecithin. I like that this lecithin is in soft capsules that are easy to swallow. If you seek natural support for your liver, brain, and heart, I recommend this product!
9
Supports brain function
3 people found this helpful
Lecithin is crucial for the body. It composes nearly half of the liver and one-third of the brain tissue. This essential nutrient supports cellular regeneration and proper brain function. Lecithin deficiency can impair drug effectiveness, so its regular intake is vital. It also assists in preventing conditions such as Alzheimer's disease.
7.5
Cardiovascular risk reduction
5 people found this helpful
The best lecithin is sunflower lecithin. It contains oleic and linoleic acids (Omega-9 fatty acids) that reduce the risk of cardiovascular diseases, enhance digestion, and improve pancreatic function. It’s especially beneficial for women undergoing menopause. The capsules are large but easy to swallow, with no taste or aroma.
8
Lecithin improves children's heart health
INTEGRATIVE MORPHOMETRIC CHARACTERISTIC OF ENDOTHELIAL DYSFUNCTION IN THE CASES OF CHILDREN WITH ESSENTIAL ARTERIAL HYPERTENSION.
We conducted an in-depth study involving 80 children diagnosed with Essential Arterial Hypertension and related endothelial dysfunction.
The children received either standard treatment or an improved regimen that included lecithin. Over two months, we observed significant benefits in heart function and reduced complications.
Those on optimized treatment showed improvements in heart volume and reduced vascular dysfunction. This suggests that lecithin can positively influence cardiovascular health in children facing these conditions.
9.5
Low LCAT activity linked to mortality
Low LCAT activity is linked to acute decompensated heart failure and mortality in patients with CKD.
We examined how lower levels of lecithin-cholesterol acyltransferase (LCAT) activity could impact cardiovascular health in patients with chronic kidney disease (CKD). This study involved 453 non-dialysis CKD patients and monitored them for about five years.
We found that low LCAT activity is linked to higher risks of death and acute decompensated heart failure, suggesting a protective role of certain HDL particles. However, interestingly, LCAT levels did not seem to affect atherosclerotic events or kidney function declines.
7
Effects of LCAT on cholesterol metabolism
Effects of Recombinant Human Lecithin Cholesterol Acyltransferase on Lipoprotein Metabolism in Humans.
In a randomized, placebo-controlled crossover study with five volunteers who had atherosclerotic cardiovascular disease, we explored the effects of increasing lecithin cholesterol acyltransferase (LCAT) activity on fat metabolism.
While we found that a short-term boost in LCAT enhances the conversion of free cholesterol into cholesteryl esters, it did not significantly change the levels of key HDL proteins or affect the metabolism of other lipoproteins.
Ultimately, although LCAT might help improve cholesterol balance over time, there wasn't a clear immediate benefit proven for heart health.
8
Lecithin shows promise for cholesterol management
MEDI6012: Recombinant Human Lecithin Cholesterol Acyltransferase, High-Density Lipoprotein, and Low-Density Lipoprotein Receptor-Mediated Reverse Cholesterol Transport.
We investigated how MEDI6012, a recombinant human lecithin cholesterol acyltransferase, could impact heart health in patients with stable coronary heart disease. In a phase 2 clinical trial, 48 participants received either MEDI6012 or a placebo, with various doses administered through intravenous and subcutaneous methods.
Our results showed that while MEDI6012 was effective at increasing high-density lipoprotein (HDL) cholesterol levels, there were no significant safety concerns compared to placebo. Overall, it appears that lecithin treatment could enhance the body’s cholesterol handling but further research is needed before it can be routinely recommended.
References
Stadler JT, Bärnthaler T, Borenich A, Emrich IE, Habisch H, et al. Low LCAT activity is linked to acute decompensated heart failure and mortality in patients with CKD. J Lipid Res. 2024;65:100624. doi:10.1016/j.jlr.2024.100624
Reyes-Soffer G, Matveyenko A, Lignos J, Matienzo N, Santos Baez LS, et al. Effects of Recombinant Human Lecithin Cholesterol Acyltransferase on Lipoprotein Metabolism in Humans. Arterioscler Thromb Vasc Biol. 2024;44:1407. doi:10.1161/ATVBAHA.123.320387
He Y, Pavanello C, Hutchins PM, Tang C, Pourmousa M, et al. Flipped C-Terminal Ends of APOA1 Promote ABCA1-Dependent Cholesterol Efflux by Small HDLs. Circulation. 2024;149:774. doi:10.1161/CIRCULATIONAHA.123.065959
Horlenko OM, Rusyn VI, Studenyak VM, Sochka NV, Horlenko FV, et al. INTEGRATIVE MORPHOMETRIC CHARACTERISTIC OF ENDOTHELIAL DYSFUNCTION IN THE CASES OF CHILDREN WITH ESSENTIAL ARTERIAL HYPERTENSION. Wiad Lek. 2021;74:948.
George RT, Abuhatzira L, Stoughton SM, Karathanasis SK, She D, et al. MEDI6012: Recombinant Human Lecithin Cholesterol Acyltransferase, High-Density Lipoprotein, and Low-Density Lipoprotein Receptor-Mediated Reverse Cholesterol Transport. J Am Heart Assoc. 2021;10:e014572. doi:10.1161/JAHA.119.014572